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Lipophilic or Hydrophilic Nature of Statins Is Important

Predominantly lipophilic statins penetrate muscle cell at a higher degree than predominantly hydrophilic statins. In addition, ...

Which Statin Is Right for My Patient? - Medscape

Lipophilic statins cross the blood-brain barrier more readily, ... Cite this article: Which Statin Is Right for My Patient? - Medscape - Aug 27, 2007. Tables.

water and lipid soluble statins - General Practice Notebook

apart from pravastatin and rosuvastatin all other available statins - atorvastatin, cerivastatin, fluvastatin, lovastatin and simvastatin - are lipophilic Metabolism ...

Discovery and development of statins - Wikipedia

Discovery and development of statins The discovery of ... The more lipophilic statins tend to achieve higher levels of exposure in non-hepatic tissues, ...

Lipophilic versus hydrophilic statin ... - Systematic Reviews

Lipophilic versus hydrophilic statin therapy for heart failure: a protocol for an adjusted indirect comparison meta-analysis

statins Flashcards | Quizlet

Lipophilic statins properties. Lower hepatoselectivity (passive in and then right back out) Bind more to serum protein Higher incidence of adverse effects

Lipophilic Statin Versus Rosuvastatin (Hydrophilic ...

1. Cardiovasc Drugs Ther. 2016 Apr;30(2):177-88. doi: 10.1007/s10557-015-6636-z. Lipophilic Statin Versus Rosuvastatin (Hydrophilic) Treatment for Heart Failure: a ...

Lipophilic tops hydrophilic statins for heart failure

(HealthDay)—For patients with heart failure, lipophilic statin is superior to hydrophilic statin for cardiac function and inflammation, according to a meta-analysis ...

Hydrophilic vs lipophilic statins in coronary artery ...

INTRODUCTION Some available experimental studies have reported that hydrophilic statins might have advantages compared with lipophilic statins in patients with ...

Lipophilic Statins and Aldosterone Secretion | Circulation

Editorials; aldosterone; mineralocorticoids; statin; Statins have been hypothesized to have pleiotropic effects that may mitigate the risks of developing arterial and ...