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Central tolerance - Wikipedia

Central tolerance is the mechanism by which newly developing T cells and B cells are rendered non-reactive to self. The concept of central tolerance was proposed in ...

T-Cell Tolerance: Central and Peripheral

T-Cell Tolerance: Central and Peripheral. Yan Xing and Kristin A. Hogquist; Center for Immunology, Department of Laboratory Medicine and Pathology, University of ...

Peripheral tolerance - Wikipedia

Peripheral tolerance is the second branch of immunological tolerance, after central tolerance. It takes place in the immune periphery (after T and B cells egress from ...

Central tolerance: learning self-control in the thymus ...

Central tolerance refers to those events in the early life of a lymphocyte that focus the adaptive immune system on pathogens and steer it away from healthy tissue.

Central B-Cell Tolerance: Where Selection Begins

The studies of central B-cell tolerance performed in the last 30 years in mice have given us an understanding of what are the general forces that shape the murine ...

A CENTRAL ROLE FOR CENTRAL TOLERANCE - annualreviews.org

AbstractRecent elucidation of the role of central tolerance in preventing organ-specific autoimmunity has changed our concepts of self/nonself discrimination. This ...

Mechanisms of tolerance induction - BNITM

Mechanisms of tolerance induction Friedrich Haag Institute of Immunology, ... • Central tolerance mechanisms regulate self-reactivity in both T and B

Immunological Tolerance - Biology Pages

Immunological Tolerance Immunological tolerance is the failure to mount an immune response to an antigen. It can be: Natural or "self" tolerance.

Central tolerance: Learning self-control in the thymus ...

Central tolerance : Learning self-control in the thymus. / Hogquist, Kristin A ... one of the main mechanisms of T-cell central tolerance is clonal deletion, ...

Figure 1 : Central tolerance: learning self-control in the ...

FIGURE 1 | Central-tolerance mechanisms. From the following article: Central tolerance: learning self-control in the thymus. Kristin A. Hogquist, Troy A. Baldwin ...


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