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Central tolerance - Wikipedia

Central tolerance is the mechanism by which newly developing T cells and B cells are rendered non-reactive to self. The concept of central tolerance was proposed in ...

T-Cell Tolerance: Central and Peripheral

Recent advances in mechanistic studies of central and peripheral T-cell tolerance are promoting the development of therapeutic strategies to treat autoimmune ...

Peripheral tolerance - Wikipedia

Peripheral tolerance is the second branch of immunological tolerance, after central tolerance. It takes place in the immune periphery (after T and B cells egress from ...

Central tolerance: learning self-control in the thymus ...

Central tolerance refers to those events in the early life of a lymphocyte that focus the adaptive immune system on pathogens and steer it away from healthy tissue.

Central Tolerance | Research | Baylor College of Medicine ...

Dr. Matthew Bettini is investigating how both central and peripheral tolerance mechanisms are crucial in preventing the onset of autoimmunity.

Central B-Cell Tolerance: Where Selection Begins

The studies of central B-cell tolerance performed in the last 30 years in mice have given us an understanding of what are the general forces that shape the murine ...

Central tolerance - Latest research and news | Nature

Central tolerance encompasses the mechanisms that render newly developing lymphocytes in primary lymphoid organs tolerant to self antigens. Developing B cells and T ...

Immunological Tolerance - Biology Pages

Immunological Tolerance Immunological tolerance is the failure to mount an immune response to an antigen. It can be: Natural or "self" tolerance.

Central tolerance: Learning self-control in the thymus ...

Central tolerance : Learning self-control in the thymus. / Hogquist, Kristin A ... one of the main mechanisms of T-cell central tolerance is clonal deletion, ...

Mechanisms of tolerance induction - BNITM

Mechanisms of tolerance induction Friedrich Haag Institute of Immunology, ... • Central tolerance mechanisms regulate self-reactivity in both T and B