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Central tolerance - Wikipedia

Central tolerance is the mechanism by which newly developing T cells and B cells are rendered non-reactive to self. The concept of central tolerance was proposed in ...

Peripheral tolerance - Wikipedia

Peripheral tolerance is the second branch of immunological tolerance, after central tolerance. It takes place in the immune periphery (after T and B cells egress from ...

T-Cell Tolerance: Central and Peripheral

CENTRAL TOLERANCE. T lymphocytes arise from circulating bone-marrow-derived progenitors that home to the thymus. After T lineage commitment and ...

Central Tolerance | Research | Baylor College of Medicine ...

Dr. Matthew Bettini is investigating how both central and peripheral tolerance mechanisms are crucial in preventing the onset of autoimmunity.

Central tolerance: learning self-control in the thymus ...

Central tolerance refers to those events in the early life of a lymphocyte that focus the adaptive immune system on pathogens and steer it away from healthy tissue.

Central tolerance : definition of Central tolerance and ...

Central tolerance is the mechanism by which newly developing T cells and B cells are rendered non-reactive to self. [1] The concept of central tolerance was proposed ...

Central and Peripheral tolerance & Autoimmunity Flashcards ...

Start studying Central and Peripheral tolerance & Autoimmunity. Learn vocabulary, terms, and more with flashcards, games, and other study tools.

How defects in central tolerance impinge on a deficiency ...

Abstract. Both central (thymic) and peripheral (nonthymic) mechanisms are important for the induction and maintenance of T cell tolerance ...

Central tolerance: Learning self-control in the thymus ...

TY - JOUR. T1 - Central tolerance. T2 - Nature Reviews Immunology. AU - Hogquist,Kristin A. AU - Baldwin,Troy A. AU - Jameson,Stephen C. PY - 2005/10

CENTRAL TOLERANCE: LEARNING SELF CONTROL IN THE THYMUS

central-tolerance mechanisms greatly reduces the threat of autoimmunity inherent in the adaptive immune system. Indeed, the significance of these processes to


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